Leo Clarke was an American television producer.

Clarke started out as a production assistant on The Redd Foxx Show and then joined It's Garry Shandling's Show as a production manager.

Clarke also produced Roc (with Charles S. Dutton), the 1995 reboot of Get Smart, Moesha (with Brandy Norwood), The Steve Harvey Show, All of Us (co-created by Will Smith and Jada Pinkett Smith), Lucky Louie (with Louis C.K. and Pamela Adlon), and Frank TV (with impressionist Frank Caliendo),

Clarke received three consecutive Emmy nominations for Outstanding Children's Program for producing the Disney Channel's Dog With a Blog.

Clarke died August 27, 2018, in San Francisco, California. He was 60.